The effect of two methods of resistance training with and without blood flow restriction on coagulation indices and blood glucose levels in type 2 diabetic patients

Introduction: Imbalance of the homeostasis system can lead to blood clot formation. The aim of this study was to investigate the effect of two resistance training methods with and without blood flow restriction on coagulation parameters and blood glucose levels in diabetic patients. Methods: 41 patients with type 2 diabetes were randomly divided into three groups of resistance training with and without blood flow restriction and the control group. The subjects of the resistance training group with and without flow restriction performed the training for 8 weeks with intensities of 20, 40, 60, 80% of one maximum repetition and 20 and 30% of one maximum repetition, respectively. During this period, the subjects in the control group led a normal life and did not have a regular exercise program. Coagulation parameters, hematocrit and blood glucose levels were measured before and 48 hours after the last training session. Analysis of variance with intergroup factor and Bonferroni post hoc test were used to evaluate the effect of intervention on quantitative factors. SPSS22 statistical software was used to analyze the data. Significance level was considered for all statistical analyzes P <0.05. Results: Prothrombin Time index in both groups of resistance training increased significantly compared to the control group (P ‹0.05); But no significant difference was observed in Partial thromboplastin time and hematocrit index (P ›0.05). Fibrinogen factor also decreased in training groups (P ‹0.05). Blood glucose decreased in the resistance training group without restriction of blood flow compared to the control group (P ‹0.05). Conclusion: Eight weeks of resistance training can prevent thrombosis and sudden onset of cardiovascular disease in patients with type 2 diabetes by reducing fibrinogen levels and increasing the Prothrombin Time index. This type of exercise also plays an insulin-like role by lowering blood sugar levels.