KEPATUHAN TERAPI KELASI BESI BERDASARKAN KADAR FERITIN PADA PENDERITA THALASSEMIA DI RUMAH SAKIT SYAMSUDIN KOTA SUKABUMI

2021 
Abstract. Thalassemia is a blood disorder that results from decreased or lost synthesis of one or more globin chains. Transfusion is indicated in thalassemia patients with an Hb level 7 g / DL. Then to prevent the presence of iron deposits in the body due to repeated transfusions, chelation therapy is needed to reduce the morbidity and mortality rates in thalassemia patients. Several studies found that patients with thalassemia who were adherent to iron chelation therapy had ferritin levels 2500μg / L. The purpose of this study was to describe the adherence of iron chelation therapy in thalassemia patients at Syamsudin SH Hospital. This research used quantitative descriptive method with cross sectional research design. The study population was 148 thalassemia patients based on medical record data with the sampling technique, namely total sampling. This study found that the sex of female 75 patients (50.7%), male gender 73 patients (49.3%), ferritin levels ≤ 2500μg / L (36.48%), ferritin levels> 2500μg / L (63.52%) with a mean ferritin level in all thalassemia patients of 4.607.79 Keywords : Chelation Therapy, Ferritin Levels µg / L. The conclusion of this study that most thalassemia patients were not adherent to taking chelation therapy. Abstrak. Thalassemia adalah kelainan darah yang terjadi akibat penurunan atau hilangnya sintesis dari satu atau lebih rantai globin. Transfusi diindikasikan pada pasien thalassemia dengan kadar Hb 2500μg/L (63,52%) dengan rerata kadar feritin pada seluruh pasien thalassemia sebesar 4.607,79μg/L. Kesimpulan dari penelitian ini sebagian besar pasien thalassemia tidak patuh dalam mengonsumsi terapi kelasi. Kata Kunci : Kadar Feritin, Terapi Kelasi
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