JAK3 inhibitor-based immunosuppression in allogeneic islet transplantation in cynomolgus monkeys

Jong Min Kim,Jun Seop Shin,Byoung-Hoon Min,Seong Jun Kang,Il Hee Yoon,Hyunwoo Chung,Ji-Yeon Kim,Eung-Soo Hwang,Jong Won Ha,Chung Gyu Park

JAK3 inhibitor-based immunosuppression in allogeneic islet transplantation in cynomolgus monkeys

2019

Jong Min Kim
Jun Seop Shin
Byoung-Hoon Min
Seong Jun Kang
Il Hee Yoon
Hyunwoo Chung
Ji-Yeon Kim
Eung-Soo Hwang
Jong Won Ha
Chung Gyu Park

ABSTRACTIslet transplantation is efficacious to prevent severe hypoglycemia and glycemic liability of selected patients of type 1 diabetes. However, since calcineurin inhibitor (CNI) causes β-cell ...

Keywords:

Internal medicine
Immunosuppression
Diabetes mellitus
Endocrinology
Transplantation
Islet
Biology
Immunology
severe hypoglycemia
Calcineurin
Glycemic
Type 1 diabetes

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