Overdiagnosis of cow's milk allergy with home reintroduction.

Cow's milk allergy (CMA) may present with IgE-mediated or non-IgE mediated symptoms (1). In the Netherlands, non-IgE mediated CMA in infants is more common (3.5%) than IgE-mediated CMA (1%) (2,3,4). For many years it has been a matter of debate which challenge is best for the diagnosis of food allergy: home reintroductions (HR), supervised open food challenges (OFC) or double-blind, placebo-controlled food challenges (DBPCFC) (5,6).