Mast Cell Degranulation and Fibroblast Activation in the Morphine-induced Spinal Mass: Role of Mas-related G Protein-coupled Receptor Signaling

Editor’s PerspectiveWhat We Already Know about This TopicThe formation of intrathecal masses complicates the use of intrathecal opioid therapy for chronic painThe degranulation of mast cells has been linked to intrathecal mass formationWhat This Article Tells Us That Is NewUsing a guinea pig model,