Defining the biological responses of IL-6 by the study of a novel IL-6 receptor chain (IL6R) immunodeficiency

Amit Nahum,Nigel Sharfe,Arnon Broides,Harjit Dadi,Zahra Naghdi,Amarilla Mandola,Linda Vong,Adi Arbiv,Ilan Dalal,Jacov Levy,Ido Brami,Ohad Wormser,Chaim M. Roifman

Defining the biological responses of IL-6 by the study of a novel IL-6 receptor chain (IL6R) immunodeficiency

2019

Amit Nahum
Nigel Sharfe
Arnon Broides
Harjit Dadi
Zahra Naghdi
Amarilla Mandola
Linda Vong
Adi Arbiv
Ilan Dalal
Jacov Levy
Ido Brami
Ohad Wormser
Chaim M. Roifman

: We describe immunodeficiency arising from ablation of IL6R expression that is characterized by recurrent infections, eczema, high IgE titers, and absent CRP acute-phase response.

Keywords:

Immunology
Interleukin-6 receptor
Immunodeficiency
Medicine
Interleukin 6
Immunoglobulin E
Recurrent infections
Titer

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations