The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery : an analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols

D. Andreou,S. Bielack,Dorothe Carrle,Matthias Kevric,R. Kotz,W. Winkelmann,Gernot Jundt,M. Werner,S. Fehlberg,Leo Kager,Thomas Kühne,Susanna Lang,Martin Dominkus,G. U. Exner,Jendrik Hardes,Axel Hillmann,V. Ewerbeck,U. Heise,Peter Reichardt,Per-Ulf Tunn

The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery : an analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols

2011

Local recurrence (LR) in osteosarcoma is associated with very poor prognosis. We sought to evaluate which factors correlate with LR in patients who achieved complete surgical remission with adequate margins.

Keywords:

Medicine
Cancer
Neoadjuvant therapy
Anatomical pathology
Pathology
Biopsy
Osteosarcoma
Sarcoma
Surgical margin
Chemotherapy regimen
Surgery

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