Abstract 873: Acetate Protects the Heart Against Ischemic Injury by Alternating TCA Cycle-related Metabolites and AMP-activated Protein Kinase

Genki Ichihara,Yoshinori Katsumata,Shinichi Goto,Seien Ko,Takahiro Hiraide,Hiroki Kitakata,Hidenori Moriyama,Kohsuke Shirakawa,Atsushi Anzai,Jin Endo,Masaharu Kataoka,Fukuda Keiichi,Motoaki Sano

Abstract 873: Acetate Protects the Heart Against Ischemic Injury by Alternating TCA Cycle-related Metabolites and AMP-activated Protein Kinase

2019

Genki Ichihara
Yoshinori Katsumata
Shinichi Goto
Seien Ko
Takahiro Hiraide
Hiroki Kitakata
Hidenori Moriyama
Kohsuke Shirakawa
Atsushi Anzai
Jin Endo
Masaharu Kataoka
Fukuda Keiichi
Motoaki Sano

Introduction: Acetate is preferentially taken up in the heart, and converted into acetyl-CoA by acetyl-CoA synthetase2 (AceCS2), which is abundant in the mitochondria of cardiomyocytes, resulting i...

Keywords:

Cardiology
AMP-activated protein kinase
Internal medicine
Diabetes mellitus
Biology
Pharmacology
Citric acid cycle
ischemic injury

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