Pulmonary-Renal Syndrome in Patients with ANCA (+) vasculitis: An Eleven- Year Single Center Experience

drome, can cause pulmonary-renal syndrome 1 . They are also frequently, up to 90%, associated with the presence of antineutrophil cytoplasmic antibodies (ANCA) 2,3 in the serum. So, these vasculities can also be divided into two major categories, those associated with antibodies against myeloperoxidase [MPO-ANCA (+)] and those against proteinase 3 [PR3-ANCA (+)] 4,5 . Respiratory involvement usually presents with hemoptysis or acute respiratory failure needed ventilatory support 6,7 , although some times a more indolent initiation of the disease can expressed. The aim of the present study was to report the clinical course and outcome in a series of patients with PRS and ANCA positive vasculitis.