A Toxicity Study of the Treatment of T3 Bladder Tumours with a Combination of Radiotherapy and Chemotherapy

18 patients with category T3 bladder cancer were treated with a combination of radical radiotherapy followed after an interval of 1-3 months by pulsed chemotherapy with adriamycin and 5-fluorouracil. Providing the chemotherapy was limited to 4 cycles, there was no serious toxicity and the regime was well tolerated.