Left ventricular thrombus and pulmonary embolism: A case series of thrombosis in COVID-19 in Thai patients

Abstract Thrombosis in COVID-19 is increasingly recognized and is generally associated with high mortality rate The key clinical question of this report was whether COVID-19 could be complicated with cardiac thrombus and pulmonary embolism in Asian population We demonstrated the case series of thrombosis in Thai patients with confirmed SARS-CoV-2 infection One case was the first case of large left ventricular thrombus and three other cases had pulmonary embolism All patients were male and they had low absolute lymphocyte count while lactate dehydrogenase level and D-dimer were markedly elevated, especially at the time when the thrombosis was diagnosed All cases had severe COVID-19 with pneumonia Two cases who needed mechanical ventilation were successfully extubated After hospitalization for 13 to 49 days, pneumonia and thrombosis improved and all of them could be discharged from the hospital Thrombosis is common in COVID-19 and could present in both arterial and venous sites even in Asian population D-dimer is a strong marker to predict thrombosis and could be a prognostic predictor for severity of COVID-19