Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis

Aubin Moutal,Sergey Kalinin,Kathy Kowal,Natalia Marangoni,Jeffrey L. Dupree,Shao Xia Lin,Kinga Lis,Lucia Lisi,Kenneth Hensley,Rajesh Khanna,Douglas L. Feinstein

Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis

2019

Aubin Moutal
Sergey Kalinin
Kathy Kowal
Natalia Marangoni
Jeffrey L. Dupree
Shao Xia Lin
Kinga Lis
Lucia Lisi
Kenneth Hensley
Rajesh Khanna
Douglas L. Feinstein

We previously showed that treatment with lanthionine ketimine ethyl ester (LKE) reduced disease severity and axonal damage in an experimental autoimmune encephalomyelitis (EAE) mouse model of multi...

Keywords:

Biology
Multiple sclerosis
Biochemistry
Conditional gene knockout
Diabetes mellitus
Experimental autoimmune encephalomyelitis
Pharmacology
Lanthionine Ketimine
Collapsin response mediator protein family
Spinal cord
Disease
disease severity
Immunology

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