Real-world Inpatient Use of Medications Repurposed for COVID-19 in U.S. Hospitals, March-May 2020

We report off-label use patterns for medications repurposed for COVID-19 at 318 U S hospitals Inpatient hydroxychloroquine use declined by 80%, while corticosteroids and tocilizumab were initiated two days earlier in May versus March 2020 Two-thirds of ventilated COVID-19 patients were already receiving corticosteroids during March-May, resembling pre-COVID use in mechanically ventilated influenza patients