Basis for Soft Tissue Repair and Healing

Soft tissue repair or healing refers to a series of pathophysiological processes in which tissues are repaired by regeneration, repair, and reconstruction after soft tissue defects (such as wounds, incisions, and wound surfaces) caused by trauma or other reasons. In essence, soft tissue repair is an inherent defensive adaptive response to the injury and defect of tissues and cells caused by various injury and pathogenic factors. Soft tissue injury and tissue defect caused by wound or tissue missing caused by extensive necrosis and tissue destruction usually needs to be repaired by regeneration and reconstruction of surrounding histocyte or by proliferation of other histocytes (usually connective histocytes) to replace the original tissue. These wounds are common in peacetime and wartime and generally can be divided into mechanical (such as incised wound and surgery), physical and chemical (such as thermal burn, frostbite, chemical skin injury, and radiation skin ulcer), inflammatory (such as abscess), ischemic (such as infarction) and metabolic (such as diabetic skin ulcer) wounds, etc., which are characterized by the formation of compensatory tissue.