Synthesis and dopamine agonist properties of (+)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol and its enantiomers

Horace A. DeWald,Thomas G. Heffner,Juan C. Jaen,David M. Lustgarten,Andrew T. McPhail,Leonard T. Meltzer,Thomas A. Pugsley,Lawrence D. Wise

Synthesis and dopamine agonist properties of (+)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol and its enantiomers

1990

Horace A. DeWald
Thomas G. Heffner
Juan C. Jaen
David M. Lustgarten
Andrew T. McPhail
Leonard T. Meltzer
Thomas A. Pugsley
Lawrence D. Wise

The dopamine agonist profile of (±)-trans-3,4,4a,10b-tetrahydro-4-pro-2H,5H-[1] benzopyrano [4,3-b]-1,4-oxazin-9-ol (16a) and its enantiomers (16b-c) was examined

Keywords:

Biochemistry
Dopamine agonist
Enantiomer
Stereochemistry
Organic chemistry
Chemistry
Phenols
Agonist
Dopamine
Antagonist
Autoreceptor
Dopamine receptor D2
Mechanism of action
Dopaminergic

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