Immune Response to Hepatitis B Vaccine in Health Care Workers in Tertiary Care Hospital in South India

Background: Hepatitis B is one of the most prevalent infectious diseases in the world. Health care workers (HCWs) are at high risk of contracting Hepatitis B virus (HBV) infection. HBV vaccination followed by confirmation of vaccine response aids to reduce the risk of attaining the Hepatitis B infection and decreasing the chances of the spread of the infection from Health care workers into the society. Aim: The aim of the study is to evaluate hepatitis B virus (HBV) immunization status and anti-HBs titre among HCWs. Materials and methods: This is a cross-sectional study conducted at the Apollo Institute of Medical Sciences and Research, Hyderabad. 200 Health care workers from different sections who were completely vaccinated with HBV vaccine were included in the study. With due consent, blood samples were collected and tested for antibody to Hepatitis B surface antigen by Chemiluminescent Microparticle Immunoassay  from May 2014 to June 2014. Titre ?10 mIU/mL was considered to be seroprotective. Statistical analysis: Statistical analysis of data was done in SPSS version 23 and p-value of