533 Study of the echocardiographic predictors for 10-year survival after thrombolytic therapy of acute myocardial infarction

s S87 Eur J Echocardiography Abstracts Supplement, December 2006 Results: Pts were divided in two groups: group I pts with FT 202 pts (26%), group II without FT 558 (74%). Left ventricle thrombi were found in 16 pts (8%) of group I and in 39 pts of group II (7%) p>0.05. In 6 pts of group I the thrombi were localized or connected to false tendon. These group of pts was treated by thrombolitics, had extensive antero-lateral MI (E?35%) and FT localized in the region of MI. Two patients of group I and 1 of group II had neurological ischemic stroke. As well we analyze frequency of thrombi occurrence dependency of therapy: PCI or thrombolitic. In group of 582 pts treated by PCI we observed thrombus in 23 (4%) cases, in 178 pts treated by thrombolitic therapy thrombi were found in 32 (18%) pts p 90 ms, E/A≤1.04, DT>150 ms). HRV indices and arrhythmic events were evaluated by 24 hour Holter monitoring (view Table; M±SD; *p <0.05). Time and frequency domain HRV indices were significantly reduced in patients with restrictive LV filling patterns compared to those with impaired LV relaxation. Early postinfarction patients with restrictive LV filling showed increased frequency of ventricular arrhythmias during the day. These findings reflect more expressed autonomous nervous imbalance and may predict higher mortality in these patients. Table 1. Correlation: HRV and LV filling patterns HRV indices and Abnormal LV relaxation Restrictive LV filling arrhythmic events (n=144) (n=57) SDNN, msec 115.8±5.48 94.03±2.34 * SDANN, msec 75.9±2.32 61. 8 ±1.47 * SDNN index, msec 51.2±3.61 50.07±l.03,n/s RMSSD, msec 27.0±2.19 22.5±1.26 * PNN50, % 7.1 ±1,38 8.1±0.91* LF, msec2 494.8±23.27 3 89.55±10.45* HF, msec2 9 3.1±7.26 7 9.66±4.86 * LF/HF 5.95±2.7 6.46±2.8* VPB, per day 45.4±10.61 70.14±26.97 * VPB pair, per day 3.02±0.84 5.04±1.76* VT, episodes per day 0.12±0.47 0.34±0.47* Heart Rate, beats/min. 65.0±2.28 79.45±1.66* VPB ventricular premature beats, VT ventricular tachicardia episode 535 Serial echocardiographical follow-up of ventricular function in patients with reperfusion for ST-elevation myocardial infarction correlations with BNP M. Dorobantu 1 ; A.G. Fruntelata 1 ; R. Onut 1 ; A. Scafa-Udriste 1 ; D. Constantinescu 1 ; M. Marinescu 1 ; A. Vasile 1 ; A. Alexandrescu 1 1Emergency Hospital of Bucharest, Cardiology Dept., Bucharest, Romania Background: Echocardiographical assessment of left ventricular ejection fraction and wall motion score index and also of ventricular long axis function, diastolic dysfunction and post-infarction remodeling is crucial for risk stratification in patients with ST-elevation myocardial infarction (STEMI). In this population, elevated brain natriuretic peptide (BNP) levels were significantly associated with adverse outcome beyond left ventricular ejection fraction (LVEF) and identified patients with survival benefit from early invasive strategy. However, correlations of BNP levels to echocardiographical measurements of ventricular function by serial follow-up to predict risk of future clinical events have not been