Early diagnosis of spina bifida : the value of cranial ultrasound markers

Ultrasonography plays an integral part in the prenatal diagnosis of neural tube defects. However, experienced sonographers with careful evaluation are successful in accurately diagnosing spina bifida only 80-90% of the time. This study was conducted to evaluate the accuracy and reliability of certain cranial ultrasound markers the «lemon sign,» cerebellar abnormalities, microcephaly, and ventriculomegaly in facilitating the diagnosis of spina bifida in patients referred for prenatal diagnosis