Lipoproteins in Choline Deficiency

Choline deficiency leads to lipomatous infiltration of the coronary arteries and to aortic sclerosis of the Moenckeberg type in young rats. In this form of experimental cardiovascular disease the total serum cholesterol and the triglyceride-bearing lipoproteins are decreased. The beta-lipoprotein classes are essentially within normal limits. The significance of these findings in particular and of serum lipid values in general as relating to different types of experimental cardiovascular disease is discussed.