FREQUENT USE OF HOUSEHOLD CLEANING SPRAYS AND DECREASES IN HEART RATE VARIABILITY IN SAPALDIA

Background and Aims: Household cleaning products are an indoor source of exposure to volatile organic compounds and toxic air contaminants. We investigated if non-professional use of household cleaning and air freshening sprays, and scented products was associated with reduced heart rate variability in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). Methods: In a cross-sectional survey, 24-hour electrocardiograms were recorded in 580 randomly selected SAPALDIA participants • 50 years of age, who also reported cleaning activities in their homes. Of the 580 participants, 515 reported use of any household spray or scented product, and 65 did not report use to any product and were considered unexposed. Adjusted average percent changes in standard deviation of all normal-to-normal intervals in 24-hours (24-hr SDNN), total power (TP), low frequency (LF), and high frequency (HF) were estimated in association with frequency (< 1, 1-3, and 4-7 days/week, unexposed as refer...