Postoperative administration of metamizole for one single day: A retrospective cohort study
2017
We read the study by Fieler et al. with great interest.
Their study addresses an important aspect of postoperative
analgesia management. They did not report any
cases of agranulocytosis following metamizole administration
in more than 1000 children. A single dose of
intravenous metamizole for treatment of postoperative
pain seems to be well tolerated without adverse events
directly related to metamizole administration. We would
like to report a retrospective cohort investigation we
performed in 2012, on consecutive adult patients, with
the aim of investigating whether postoperative intravenous
metamizole leads to agranulocytosis.
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