2- (3-cyano-4-alkoxy) phenyl-4-thiazole-5-carboxylic acid substituted compounds, compositions, and preparation and use

The present invention relates to 2 having a xanthine oxidase inhibitory activity of the Formula I as shown in (3-cyano-4-alkoxy) phenyl-4-thiazole-5-carboxylic acid substituted compounds, compositions and production method, the present invention further relates to their preparation and treatment (or) prevention of hyperuricemia and gout medicaments. Formula I: R2 is a substituted or unsubstituted phenyl group, a substituted or unsubstituted aromatic heterocyclic group; Rl is an optionally substituted aliphatic hydrocarbon group, straight-chain or branched, substituted or unsubstituted alicyclic hydrocarbon group, a substituted or a substituted aryl group; a is an oxygen atom, a sulfur atom or a nitrogen atom.