Expected PSA and Biochemical Control with Prostate SBRT Compared to Conventional Fractionated Radiotherapy

Prostate specific antigen (PSA) is a serum marker used to monitor biochemical control after prostate cancer treatment. The kinetics of PSA after prostate SBRT differs from standard radiation (RT). In this chapter, we summarize and discuss the differences in expected PSA nadir, rate of decay, and PSA bounce as well as biochemical control after SBRT versus standard RT to the prostate.