Temporal Reverse Flow by Proximal Femoral Artery Occlusion during Drug-coated Balloon Dilatation: A Technique to Minimize Downstream Particle Embolization and Systemic Adverse Effects

Abstract Downstream paclitaxel particle embolization for non-healing ischemic ulcers and systemic adverse effects caused by a paclitaxel drug-coated balloon are of concern, and safety measures to prevent these adverse risks are needed. To reduce distal particle embolization and movement of the paclitaxel particles to systemic blood flow during drug-coated balloon inflation, proximal balloon occlusion using a sheathless temporary occlusion balloon-guiding catheter and extraction by manual aspiration of the paclitaxel containing blood through the catheter are good treatment options to overcome these risks. Here, we introduce this method with tips and tricks, and demonstrate initial experience of this technique.