Povezanost veličine, smještaja i histoloških karakteristika duktalnoga invazivnoga karcinoma s termografskim karakteristikama dojke

Introduciton: Invasive breast carcinoma is the most common oncologic disease worldwide. Current radiologic diagnostic capabilities generally detect only morphologic changes. Therefore, it is important to fulfill the morphologic diagnostic examinations with a new complementary method that focuses on characteristics other than morphology such as electromagnetic changes produced by cancer, which is the basis of thermography. ----- Materials and methods: The research was conducted at the University Hospital Center Zagreb, Croatia between October 2017 and August 2018. 112 adult female patients with an indication for a core biopsy due to a suspicious breast mass were included in the study. All of them underwent breast thermography. The data collected was statistically analyzed to determine how tumour size, distance from the skin and its histologic characteristics influence breast thermographic properties. ----- Results: In patients with ductal invasive breast cancer, the status of estrogen, progesterone, HER2 receptors and Ki67 values did not have a statistically significant effect on the difference in temperatures between diseased and healthy breasts. Breasts that have a tumor were found to have a statistically greater Tmax compared to the tumor-free breast. In this research the only factor which produced a significant change in thermographic characteristics in the diseased breast compared to the healthy breast was a minimal area of the largest cross-sectiona length of at least 460mm2. As none of the other parameters studied showed a statistically significant correlation, they cannot be used for scientific research or the detection of breast cancer and therefore it can be concluded that thermography is not a reliable method for the dectection of invasive ductal breast carcinoma in women.