Amide proton transfer–weighted MRI can detect tissue acidosis and monitor recovery in a transient middle cerebral artery occlusion model compared with a permanent occlusion model in rats

Ji Eun Park,Seung Chai Jung,Ho Sung Kim,Ji-Yeon Suh,Jin Hee Baek,Chul-Woong Woo,Bumwoo Park,Dong Cheol Woo

Amide proton transfer–weighted MRI can detect tissue acidosis and monitor recovery in a transient middle cerebral artery occlusion model compared with a permanent occlusion model in rats

2019

Ji Eun Park
Seung Chai Jung
Ho Sung Kim
Ji-Yeon Suh
Jin Hee Baek
Chul-Woong Woo
Bumwoo Park
Dong Cheol Woo

Objectives To assess whether increases in amide proton transfer (APT)–weighted signal reflect the effects of tissue recovery from acidosis using transient rat middle cerebral artery occlusion (MCAO) models, compared to permanent occlusion models.

Keywords:

Radiology
Acidosis
Middle cerebral artery
Magnetic resonance imaging
Medicine
Cardiology
Internal medicine
Occlusion
In vivo magnetic resonance spectroscopy
Effective diffusion coefficient
Ischemia
Cerebral blood flow
Penumbra

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