Minocycline-induced discolouration of the sclerae

Summary We report two patients with minocycline-induced pigmentation of the sclerae. Cutaneous pigtnentution is a well-recognized complication of minocycline therapy, but only live cases of pigimentation of the sclerae have been described previously. These five patients have a number of features in common with the two reported here. We propose that these patients represent the most severe end of the spectrum of minocycline-induced cutaneous changes. Patients should be warned about the possibility of the occurrence of pigmentary changes before starting therapy.