Nasal closure for the treatment of epistaxis secondary to hereditary hemorrhagic telangiectasia.

Abstract Hereditary hemorrhagic telangiectasia (HHT), also known by the eponym Osler-Weber-Rendu syndrome, is an autosomal dominant disorder characterised by the presence of multiple arteriovenous malformations (AVMs) affecting multiple organs. Many procedures have been used for epistaxis control in patients with this disorder. The objective of this study was to report the treatment of severe HHT-related epistaxiswith the modified Young's procedure. Materials and methods We describe the treatment of 4 patients with severe blood-transfusion-dependent epistaxis who underwent a modified Young's procedure in a tertiary hospital. The nasal closure was bilateral and complete in all cases. All patients were followed for 12 months or longer. Results The procedure was well tolerated and complete cessation of bleeding was achieved in all the patients. Conclusion Young's technique is a safe surgical procedure, well tolerated by patients with severe epistaxis and HHT.