Cognitive effects of interictal epileptiform discharges in children

Abstract Frequent interictal epileptiform discharges (IEDs) may have effects on cognition. We analysed a group of 182 children with different epilepsy syndromes, all of whom had IEDs that did not result in observed seizures, with 24-h ambulatory EEG and cognitive tests. The IED index was estimated, in wakefulness and in sleep, as percentage of time in five categories (0%,