Prevalence of vitamin D deficiency: cross-sectional study of a hospital cohort of HIV-1 infected outpatients

Background: To examine the prevalence and causal factors of vitamin D deficiency among HIV-1 infected patients and specially to assess whether antiretroviral drugs interfere with vitamin D metabolism. Methods: We performed a cross-sectional study of a hospital cohort (n=147) of HIV-1 infected outpatients followed-up by the same physician. Data were collected between January 2008 and January 2010. We draw samples for the measurement of 25(OH)D3, PTHi, serum calcium, serum phosphate, alkaline phosphatase, CD4+ cell count and viral load. Data on age, sex, VIH infection risk group, weight, height, skin color, time since HIV diagnosis, duration and stage of the infection (according to CDC 1983 staging system), as well as duration of typo of antiretroviral therapy (ART). A nutrition specialist of the same hospital performed a survey of sunlight exposition and daily vitamin D intake. We performed bi- and multivariant analysis to identify risk factor related to vitamin D deficiency (25(OH)D l<20 µg/L). Supplement: Abstracts of the Tenth International Congress on Drug Therapy in HIV Infection http://www.biomedcentral.com/content/pdf/1758-2652-13-S4-info.pdf Conference: Tenth International Congress on Drug Therapy in HIV Infection 7-11 November 2010 Glasgow, UK (Published: 8 November 2010) doi:10.1186/1758-2652-13-S4-P101 Cite this article as: Cervero et al.: Prevalence of vitamin D deficiency: cross-sectional study of a hospital cohort of HIV-1 infected outpatients. Journal of the International AIDS Society 2010 13(Suppl 4):P101. Full text: PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112875/