Can CT and MRI features differentiate benign from malignant meningiomas

AIM To highlight magnetic resonance imaging (MRI) and computed tomography (CT) characteristics in distinguishing benign from high-grade meningiomas (World Health Organization [WHO] grade II and III) preoperatively. MATERIALS AND METHODS Seventy-one patient who underwent surgical resection of intracranial meningiomas at American University of Beirut Medical Center between 2008 and 2017 were evaluated for various CT and MRI features. The correlation between imaging findings, histopathological grading, and operative reports was analysed via univariate and multivariate logistic regression analysis. MRI specificity and sensitivity in detecting meningioma brain invasion as compared to operative reports post-resection was detected. RESULTS Univariate analysis results showed a significant correlation between high-grade meningiomas and several MRI features including tumour size and volume (p=0.002,0.02), heterogeneous enhancement (p CONCLUSION MRI has a promising role in predicting meningioma grade prior to resection, which can directly impact patients' management protocols regarding surgical planning and complications.