A new diagnostic method based on RT-PCR and CLART technology for non-small cell lung cancer (NSCLC) to detect major EML4-ALK and ROS.1 translocations: CLART CMA ALK and ROS.1.

Nuria Manjon,Jaime Martínez,Gonzalo Garcia,Ana Aragon,Jaime Carrillo,José Luis Rodríguez-Peralto,José Ramón Antúnez López,Javier Hernández Losa,Rosario Cospedal,Maria Luisa Villahermosa

A new diagnostic method based on RT-PCR and CLART technology for non-small cell lung cancer (NSCLC) to detect major EML4-ALK and ROS.1 translocations: CLART CMA ALK and ROS.1.

2017

Nuria Manjon
Jaime Martínez
Gonzalo Garcia
Ana Aragon
Jaime Carrillo
José Luis Rodríguez-Peralto
José Ramón Antúnez López
Javier Hernández Losa
Rosario Cospedal
Maria Luisa Villahermosa

e20045Background: EML4-ALK and ROS1 translocations represent 3-6% and 1-2% of NSCLC patients, respectively. These patients would benefit for a tyrosine kinase inhibitor therapies. Currently, the go...

Keywords:

non-small cell lung cancer (NSCLC)
Chromosomal translocation
Pathology
Cancer research
Real-time polymerase chain reaction
Medicine
diagnostic methods
ROS1
Tyrosine-kinase inhibitor

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