Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling

2012

目的: bisoprolol 并且到当模特儿开发并且评估整个身体的生理地基于的 pharmacokinetic (WB-PBPK ) 与肾的功能缺陷在健康成年人和病人模仿它的暴露和布置。

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