The effect of platelet-rich plasma on female androgenetic alopecia: a randomized controlled trial

Abstract Background Platelet-rich plasma (PRP) may be a useful treatment for androgenetic alopecia (AGA), although objective studies are needed. Objective To determine whether PRP injections improve female AGA. Method Prospective, randomized controlled trial of 30 females diagnosed with AGA. Patients received subdermal scalp injections of Eclipse system PRP or placebo saline at weeks 0, 4 and 8. Outcome measures were changes in hair density (hair/cm2), hair caliber (mm), and blinded global photographic assessment (improved or not improved) at week 24. Results Blinded global photographic assessment indicated that 57% of PRP patients vs. 7% of saline patients improved at week 24 from baseline (p Limitations Two patients lost to follow-up. Conclusion PRP with the Eclipse system is a safe and effective intervention for female AGA.