Effect of Lopinavir and Nevirapine Concentrations on Viral Outcomes in Protease Inhibitor-experienced HIV-infected Children.

Retsilisitsoe R. Moholisa,Michael Schomaker,Louise Kuhn,Sandra Castel,Lubbe Wiesner,Ashraf Coovadia,Renate Strehlau,Faeezah Patel,Francoise Pinillos,Elaine J. Abrams,Gary Maartens,Helen McIlleron

Effect of Lopinavir and Nevirapine Concentrations on Viral Outcomes in Protease Inhibitor-experienced HIV-infected Children.

2016

Retsilisitsoe R. Moholisa
Michael Schomaker
Louise Kuhn
Sandra Castel
Lubbe Wiesner
Ashraf Coovadia
Renate Strehlau
Faeezah Patel
Francoise Pinillos
Elaine J. Abrams
Gary Maartens
Helen McIlleron

Background Adequate exposure to antiretroviral drugs is necessary to achieve and sustain viral suppression. However, the target antiretroviral concentrations associated with long term viral suppression have not been adequately defined in children.

Keywords:

Virology
Immunology
Protease
Lopinavir
Nevirapine
Medicine
Viremia
Stavudine
Hazard ratio
Viral load
Internal medicine
Lamivudine
Gastroenterology
Ritonavir

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