The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts

Anne-France Le Rolle,Thang K. Chiu,Michael Fara,Jinru Shia,Zhaoshi Zeng,Martin R. Weiser,Philip B. Paty,Vi K Chiu

The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts

2015

Anne-France Le Rolle
Thang K. Chiu
Michael Fara
Jinru Shia
Zhaoshi Zeng
Martin R. Weiser
Philip B. Paty
Vi K Chiu

Background Clinical therapy for metastatic colorectal cancer (CRC) remains limited, especially when the tumor harbors a KRAS mutation. This study aimed to identify prognostic biomarkers in CRC that are accessible for therapeutic inhibition.

Keywords:

Young adult
Colorectal cancer
Tumor microenvironment
CXCL1
Immunology
KRAS
Cancer research
Carcinogenesis
Biomarker (medicine)
Survival analysis
Medicine

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