Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects

Rajesh Kumar,L. Keoki Williams,Atsushi Kato,Edward L. Peterson,Silvio Favoreto,Katie Hulse,Deli Wang,Kenneth B. Beckman,Shannon Thyne,Michael LeNoir,Kelley Meade,David E. Lanfear,Albert M. Levin,David Favro,James J. Yang,Kevin B. Weiss,Homer A. Boushey,Leslie C. Grammer,Pedro C. Avila,Esteban G. Burchard,Robert P. Schleimer

Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects

2012

A BAFF polymorphism is associated with asthma exacerbations and serum BAFF levels. BAFF expression in vivo increases in natural rhinovirus infection. BAFF may play a role in airway antiviral immunity and impact asthma exacerbation rates.

Keywords:

Immunity
Tumor necrosis factor alpha
B-cell activating factor
Asthma
Genetic variation
Polymorphism (computer science)
Exacerbation
Immunology
Asthma exacerbations
Medicine
african american
tnf family
antiviral immunity

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