EFFECT OF FUSARIC ACID (A DOPAMINE β‐HYDROXYLASE INHIBITOR) ON PHAEOCHROMOCYTOMA

SUMMARY Fusaric acid, an inhibitor of dopamine β-hydroxylase, which converts dopamine to noradrenaline, lowered the blood pressure and induced a subjective improvement in patients with phaeochromocytoma. These effects may be due either to an impairment of catecholamine biosynthesis or to a direct action on the blood vessels. The use of this drug in the treatment of patients with inoperable malignant phaeochromocytoma or neuroblastoma may improve symptoms and prolong survival.