Exercise Oscillatory Ventilation is Independently Associated with Right Ventricular Systolic Dysfunction in Patients with Chronic Heart Failure

Background Exercise Oscillatory Ventilation (EOV) is a crucial marker for disease severity and prognosis in chronic heart failure (HF) patients. Although the presence of EOV in chronic HF patients has been demonstrated the association with worse left ventricular (LV) function, the evidence regarding with right ventricular (RV) function is still lacking. This study aim was to determine the association of EOV and RV systolic function in chronic heart failure patients. Method We retrospectively analyzed a cardiopulmonary exercise stress testing (CPET) database in 709 chronic HF patients at Cleveland Clinic, between April 2018 and June 2019. RV systolic dysfunction was determined by tricuspid annular plane systolic excursion (TAPSE) Results The prevalence of EOV in chronic HF patients with RV systolic dysfunction was significantly higher than those without RV systolic dysfunction (75.7% vs. 24.3%, p Conclusion In the large contemporary cohort, exercise oscillatory ventilation was independently associated with RV systolic dysfunction in chronic heart failure patients.