Adjuvant Chemotherapy Following Radical Radiotherapy in T3 Bladder Carcinoma

The results of treatment of deeply infiltrating bladder cancers (T3 in the UICC classification or B2 and C in the American classification) are dismal, whatever the method of treatment of the local disease. No matter whether the primary treatment is radiotherapy [12, 14], surgery [13] or a combination [14], 40% of patients die within 12 months, about 50% in 2 years, and about 70% within 5 years (Fig. 1).