Biological role of miR-204 and miR-211 in melanoma.

In this short report, we pinpoint some technical and conceptual flaws that we found in the article entitled “miR-204-5p and miR-211-5p contribute to BRAF inhibitor resistance in melanoma” (Diaz-Martinez et al., Cancer Research 2018). We also discuss how, in our opinion, these flaws led Diaz-Martinez and colleagues to incorrect conclusions about the biological role that miR-204 and miR-211 play in melanoma and about the terms of their involvement in the phenomenon of resistance to BRAF inhibitors.