Phase Formation Study of BaFe12O19 in Bioactive Glass by Modified Processing Technique

In this work, bioglass ceramics have been successfully fabricated by the modified incorporation method. In this method, solid-state reaction and conventional glass-melting techniques were employed to separately prepare barium hexaferrite (BaFe12O19: BF) and 45S5 bioactive glass powders. The mixture of BF and 45S5 glass powder was then re-melted at 1300 degrees C to form base glass. In order to change the prepared glass to glass-ceramic samples, a heat treatment technique was employed at temperatures ranging between 695 and 768 degrees C. The results confirmed the occurrence of Na6Ca(3)Si6O18, BaFe12O19 and Fe(2)O(3) phases in prepared glass ceramics. It was found that BF addition caused an alteration in magnetic behavior from soft to hard. For bioactivity assessment, the samples were soaked in simulated body fluid (SBF) for 14 days. An apatite layer was found on the surfaces of glass-ceramics confirming their bioactivity. In addition, biocompatibility was assessed by MTT (3,[4,4-dimethy thiazol-2-yl]-2,5-diphenyl-tetrazolium bromide) assay which showed that the ferrimagnetic bioactive glass-ceramics had good cytocompatibility and no cytotoxicity.