Comparison of three bioinformatics pipelines for DNA/RNA data processing

Most of the genetic instructions like growth, development, functioning, reproduction of all human beings are carried out by DNA molecule. The DNA and RNA are both nucleic acids, which contains proteins, carbohydrates, and one of three major types of macromolecule that are essential for all forms of life. In this project, we take the samples of the DNA and do testing and data processing with it. During the process for alignment and variant calling for DNA, we use three types of aligners and three variant callers. The aligners are BWA, BOWTIE, and SNAP. The variant callers are SAMtools.