A novel approach towards dethioacetalization reactions with H2O2–SOCl2 system

Abstract A simple and efficient protocol for the deprotection of dithioacetal, 1,3-dithianes and 1,3-dithiolanes has been developed using H 2 O 2 –SOCl 2 reagent system. In addition to the absence of overoxidation products for oxidation-prone substrates, high chemoselectivity, the low cost and availability of the reagents, simplicity of the method, short reaction times, and excellent yields can also be considered as strong points for this method.