A rare cause of wheeze in a young adult

Answers on p 547. A 16 year old Irish girl was referred by her general practitioner to the respiratory outpatient clinic with a nine year history of wheeze on exertion, which was getting progressively worse. She had a minimal response to regular inhaled low dose corticosteroids and required short acting β-agonists. There was no history of cough, sputum production, or haemoptysis. Her past medical history was unremarkable, …