Impact of Hemoglobin S Trait on Cell Surface Antibody Recognition of Plasmodium falciparum-Infected Erythrocytes in Pregnancy-Associated Malaria

Margaux Chauvet,Marilou Tétard,Gilles Cottrell,Florentin Aussenac,Emeline Brossier,Luc Denoyel,Marion Hanny,Murielle Lohezic,Jacqueline Milet,Nicaise Tuikue Ndam,Damien Pineau,Jocelyne Roman,Adrian J. F. Luty,Benoît Gamain,Florence Migot-Nabias,Anaïs Merckx

Impact of Hemoglobin S Trait on Cell Surface Antibody Recognition of Plasmodium falciparum-Infected Erythrocytes in Pregnancy-Associated Malaria

2019

Margaux Chauvet
Marilou Tétard
Gilles Cottrell
Florentin Aussenac
Emeline Brossier
Luc Denoyel
Marion Hanny
Murielle Lohezic
Jacqueline Milet
Nicaise Tuikue Ndam
Damien Pineau
Jocelyne Roman
Adrian J. F. Luty
Benoît Gamain
Florence Migot-Nabias
Anaïs Merckx

Background Sickle cell trait (HbAS) confers partial protection against malaria by reducing the adhesion of Plasmodium falciparum-infected erythrocytes to host receptors, but little is known about its potential protection against placental malaria.

Keywords:

Medicine
Virology
Plasmodium falciparum
Hemoglobin S trait
Cell
Pregnancy-associated malaria
Antibody
Population
Immunology
Hemoglobin
Malaria
Sickle cell trait
Thalassemia

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