Eosinophilic granuloma of the mandible: Report of a case and finding of the electoric microscope

A case of eosinophilic granuloma occuring in the mandibular bone of a 5-year-old boy was reported.He complained of a gradually increased swelling with pain in the mandibular bone. Orthopantomography showed an irregular radiolucency in the left mandibular angle.The diagnosis was established by needle biopsy from oral lesion. He was treated with combination chemotherapy of predonine and vinblastin and surgical extirpation.The extirpated material was examined histopathologically and electron-microscopically.Histopathologially, the eosinocyte infiltrate and histiocyte increased in the connective tissue, but Langerhans cell granules were not observed.These findings were described in this paper.