One-arm Study on the Preventive Effect of Traditional Chinese Medicine on Close Contacts of Patients with Novel Coronavirus Pneumonia/ 中药对新型冠状病毒肺炎患者密切接触者预防作用的单臂研究

Objective to provide the novel coronavirus pneumonia patients with close contact with Chinese medicine to prevent the decoction, observe the diagnosis of the close contacts during the 14 day isolation period, and evaluate the preventive effect of Chinese medicine on close contacts Methods a total of novel coronavirus pneumonia patients who were closely contacted in Shandong province from February 9, 2020 to February 18, 2020 were given a decoction of Chinese medicine to prevent the decoction They were given the medicine from the day of inclusion and took 5 days in a row Prescription composition: Astragalus membranaceus 10g, fried Atractylodes macrocephala 10g, Fangfeng 10g, honeysuckle vine 15g, Forsythia suspensa 10g, Scutellaria baicalensis 10g, bupleurum 10g, Pinellia ternata 6G, Huoxiang 10g, tangerine peel 6G, Poria cocos 15g, Radix Glehniae 6G, ginger 10g, decocted, two bags a day, 200ml in each bag, take one bag in the morning and evening, and fill in the medication information voluntarily by scanning the code registration The nucleic acid detection and incidence of close contacts during 14 days of isolation and observation were followed up to calculate the effective rate of traditional Chinese medicine prevention Results as of February 18, 689 close contacts were registered by scanning the code There were 392 males (56 89%) and 297 females (43 11%);the average age was (27 91 ± 14 80) years (range 3-77 years) 689 people came from 16 cities in Shandong Province There were 644 people (93 47%) with one way of contact, 36 (5 22%) with two ways of contact, 7 (1 02%) with three ways of contact, and 2 people (0 29%) with five ways of contact By comparing with the reported cases by Shandong CDC as of March 3, only one case was found, and this case was asymptomatic with positive nucleic acid test Traditional Chinese medicine has a high effective rate Conclusion prevention of novel coronavirus pneumonia by traditional Chinese medicine prevention and prevention measures can prevent the occurrence of new coronavirus pneumonia It is suggested that timely use of Chinese medicine in such public health events can effectively reduce the conversion rate of close contacts to patients with confirmed diagnosis, and it is of great significance to reduce the medical burden, social burden and financial burden of the whole society