Single Nucleotide Polymorphisms of the Angiotensin-Converting Enzyme (ACE) Gene Are Associated with Essential Hypertension and Increased ACE Enzyme Levels in Mexican Individuals

Nancy Martínez-Rodríguez,Carlos Posadas-Romero,Teresa Villarreal-Molina,Maite Vallejo,Leonardo del Valle Mondragón,Julián Ramírez-Bello,Adán Valladares,Miguel Cruz López,Gilberto Vargas-Alarcón

Single Nucleotide Polymorphisms of the Angiotensin-Converting Enzyme (ACE) Gene Are Associated with Essential Hypertension and Increased ACE Enzyme Levels in Mexican Individuals

2013

Nancy Martínez-Rodríguez
Carlos Posadas-Romero
Teresa Villarreal-Molina
Maite Vallejo
Leonardo del Valle Mondragón
Julián Ramírez-Bello
Adán Valladares
Miguel Cruz López
Gilberto Vargas-Alarcón

Aim To explore the role of the ACE gene polymorphisms in the risk of essential hypertension in Mexican Mestizo individuals and evaluate the correlation between these polymorphisms and the serum ACE levels.

Keywords:

Essential hypertension
Haplotype
Angiotensin-converting enzyme
Blood pressure
Allele frequency
Allele
Single-nucleotide polymorphism
Endocrinology
Genetics
Internal medicine
Biology
Diabetes mellitus

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