Conventional and Moderately Hypofractionated Radiation Therapy for Prostate Cancer

External beam radiation therapy (EBRT) is a common treatment modality for localized prostate cancer and may be used alone or in conjunction with other treatment modalities. In this chapter, we review conventionally fractionated and hypofractionated treatment schedules, appropriate patient selection considerations, treatment planning, patient follow-up, outcomes of treatment, and side effect management.